Traditionally when setting up SSL for an IIS website, you could generate a CSR using IIS to provide to your relevant certificate authority.
If setting up a website using the Azure App Service, the approach is slightly different. There's a myriad of ways of can do this, however this is the easiest approach I've found.
So what do you do if you come across this error in Visual Studio?
System.Security.SecurityException: Request for the permission of type ‘System.Web.AspNetHostingPermission, System, Version=188.8.131.52, Culture=neutral, PublicKeyToken=b77a5c561934e089' failed.
The error typically occurs when you download files from an external source into your Visual Studio project. Windows will recognise the file came from an external source and restrict permissions.